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Structure paper

TitleStructural Basis of Transcription of the Hachimoji Eight-Letter Alphabet by E. coli RNA Polymerase
Journal, issue, pagesTo Be Published
Publish dateDec 16, 2025 (structure data deposition date)
AuthorsQingrong L / Seteven AB / Dong W
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.6 - 2.75 Å
Structure data

74513

9zp1

EMDB-74513, PDB-9zp1:
E. coli RNA polymerase elongation complex containing the unnatural dP:Z*TP base pair in a trigger-loop-open conformation (a).
Method: EM (single particle) / Resolution: 2.6 Å

74514

9zp2

EMDB-74514, PDB-9zp2:
E. coli RNA polymerase elongation complex containing the unnatural dP:Z*TP base pair in a trigger-loop-open conformation (b).
Method: EM (single particle) / Resolution: 2.64 Å

74515

9zp3

EMDB-74515, PDB-9zp3:
E. coli RNA polymerase elongation complex containing the unnatural dP:Z*TP base pair in a trigger-loop-closed conformation.
Method: EM (single particle) / Resolution: 2.75 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

PDB-1c49:
STRUCTURAL AND FUNCTIONAL DIFFERENCES OF TWO TOXINS FROM THE SCORPION PANDINUS IMPERATOR

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsTRANSCRIPTION/DNA/RNA / E. coli RNA polymerase elongation complex containing the unnatural dP:Z*TP base pair in a trigger-loop-open conformation (a) / TRANSCRIPTION / TRANSCRIPTION-DNA-RNA complex / E. coli RNA polymerase elongation complex containing the unnatural dP:Z*TP base pair in a trigger-loop-open conformation (b) / E. coli RNA polymerase elongation complex containing the unnatural dP:Z*TP base pair in a trigger-loop-closed conformation

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