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TitleCryo-EM structure of PGT121 Fab and Rhesus macaque Ab4 Fab in complex with HIV-1 Env trimer BG505 SOSIP.664
Journal, issue, pagesTo Be Published
Publish dateAug 19, 2025 (structure data deposition date)
AuthorsChandravanshi M / Tolbert WD / Pazgier M
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.01 Å
Structure data

72206

9q3s

EMDB-72206, PDB-9q3s:
Cryo-EM structure of PGT121 Fab and Rhesus macaque Ab4 Fab in complex with HIV-1 Env trimer BG505 SOSIP.664
Method: EM (single particle) / Resolution: 3.01 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • human immunodeficiency virus 1
  • macaca mulatta (Rhesus monkey)
  • homo sapiens (human)
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / HIV-1 Env / Broadly-neutralizing antibodies (bNAbs) / glycan hole / CD4-binding site (CD4bs) / VIRAL PROTEIN / VIRAL PROTEIN-IMMUNE SYSTEM complex

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