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TitleConformational changes of a Drosophila heterotrimeric ENaC channel complex PPK1/PPK26 triggered by binding of its ligand, the endogenous wound signal peptide Vulnusin
Journal, issue, pagesTo Be Published
Publish dateAug 11, 2025 (structure data deposition date)
AuthorsJin P / Guo Y / Koepping L / Jan L / Jan YN / Feng S
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.86 Å
Structure data

72073

9pzn

EMDB-72073, PDB-9pzn:
heterotrimeric ENaC channel complex PPK1/PPK26/PPK26
Method: EM (single particle) / Resolution: 2.86 Å

72074

9pzo

EMDB-72074, PDB-9pzo:
heterotrimeric ENaC channel complex PPK1/PPK26/PPK26 with Vulnusin
Method: EM (single particle) / Resolution: 2.86 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-NH4:
AMMONIUM ION

Source
  • drosophila melanogaster (fruit fly)
KeywordsNEUROPEPTIDE / PPK / ENaC / ASIC / Ion channel / Sodium channel / Vulnusin / nociception / nociceptors / ligand / nociceptor

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