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Showing 1 - 20 of 124,506 items (all data)
-Protein Engineering-Enabled Cryo-EM Investigation of Small GTPases.
J Mol Biol, Vol. 438, Issue 17, Page 169860, Year 2026
Zhengshan Hu / Unnatiben Rajeshbhai Patel / Eliezra Glasser / Akiko Koide / Shohei Koide
Methods: EM (single particle)
-Cryo-EM Structure of the Human Mas Receptor Reveals N-terminal Occlusion of the Orthosteric Ligand Binding Pocket.
J Mol Biol, Vol. 438, Issue 16, Page 169844, Year 2026
Shota Suzuki / Kotaro Tanaka / Kouki Nishikawa / Yoshinori Fujiyoshi
Methods: EM (single particle)
-Selective Inhibition of KRASG13C Reveals an Increased Dependence on Wild-Type RAS Isoforms in Codon 13 RAS-Mutant Cancers.
Cancer Discov, Year 2026
Seamon, K.J. / Zhuang, Y. / Yang, Y.C. / Chakraborty, S. / Cregg, J. / Tomlinson, A.C.A. / Gould, A. / Ahler, E. / Maldonato, B.J. / Spradlin, J.N. ...Seamon, K.J. / Zhuang, Y. / Yang, Y.C. / Chakraborty, S. / Cregg, J. / Tomlinson, A.C.A. / Gould, A. / Ahler, E. / Maldonato, B.J. / Spradlin, J.N. / Pota, K. / Weller, C. / Marquez, A. / Wang, Z. / Koltun, E.S. / Knox, J.E. / Gill, A.L. / Smith, J.A.M. / Singh, M. / Jiang, J. / Wildes, D. / Holderfield, M.
Methods: X-ray diffraction
-Assembly and Flexibility of Borrelia burgdorferi Periplasmic HtrA Hexamers.
J Mol Biol, Vol. 438, Issue 14, Page 169813, Year 2026
Anil Kumar Shakya / D Travis Gallager / Vipin Singh Rana / Suruchi Singh / S Saif Hasan / Utpal Pal / Osnat Herzberg
Methods: EM (single particle) / X-ray diffraction
-Crystal structure of SARS-CoV-2 Papain-Like protease (PLpro) C111S mutant with active-site phosphate
To Be Published,
Arya, R. / Ganesh, J. / Prashar, V. / Kumar, M.
Methods: X-ray diffraction
-Cryo-EM structure of RubisCO from Nitrosospira multiformis.
Biochem Biophys Res Commun, Vol. 822, Page 153886, Year 2026
Yoshiki Tanaka / Yuki Nishigaya
Methods: EM (single particle)
-Crystal structure of SARS-CoV-2 Papain-Like protease (PLpro) C111S mutant with active-site sulfate
To Be Published,
Arya, R. / Ganesh, J. / Prashar, V. / Kumar, M.
Methods: X-ray diffraction
-Crystal structure of Cysteine-dependent hydrolases (CsdH) from Rhodococcus opacus in complex with Catechol
To Be Published,
Aggarwal, S. / Singh, S. / Jangid, K. / Aggarwal, D. / Sharma, A.K. / Kumar, P.
Methods: X-ray diffraction
-Crystal structure of PIM1 kinase in complex with compound 20
to be published,
Zhubi, R. / Schroeder, M. / Kalampaliki, A. / Knapp, S. / Kraemer, A. / Structural Genomics Consortium
Methods: X-ray diffraction
-Crystal structure of a Lysine--tRNA ligase (LysRS) from Pseudomonas aeruginosa
To be published,
Lanyi Lari, N. / Ung, A.R. / Lovell, S. / Cooper, A. / Battaile, K.P.
Methods: X-ray diffraction
-N-terminally modified GLP1R agonists drive G protein bias via extracellular loop 3 displacement
To Be Published,
Zhao, L. / Yuan, Q.
Methods: EM (single particle)
-Effect of Chemically Activated L-Nucleotides on Nonenzymatic RNA Copying
To Be Published,
Essex, J. / Jia, X. / Zhang, J. / Szostak, J.W.
Methods: X-ray diffraction
-Effects of Chemically Activated L-Nucleotides on Nonenzymatic RNA Copying
To Be Published,
Essex, J. / Jia, X. / Zhang, J. / Szostak, J.W.
Methods: X-ray diffraction
-SpyCEP dismantles neutrophil immunity via disorder-driven chemokine remodeling and GAG targeting
PNAS, Year 2026
Lau, R.J. / Giblin, S.P. / Sugar, A. / Di Maio, A. / Tassini, G. / Huse, K. / Chorev, D. / Chen, Y. / Wu, G.H.Y. / Huemer, C.B. ...Lau, R.J. / Giblin, S.P. / Sugar, A. / Di Maio, A. / Tassini, G. / Huse, K. / Chorev, D. / Chen, Y. / Wu, G.H.Y. / Huemer, C.B. / Kim, S.Y. / Matthews, J. / Muloud, B. / Chen, L. / McKenna, S. / Xu, Y. / Massai, L. / Muzzi, C. / Ferhati, X. / Necchi, F. / Moriel, D.G. / Feizi, T. / Liu, Y. / Pease, J.E. / Sriskandan, S. / Matthews, S.
Methods: EM (single particle)
-Crystal structure of a large ribosomal subunit protein bL17 from Bordetella pertussis
To be published,
Lanyi Lari, N. / Ung, A.R. / Lovell, S. / Battaile, K.P.
Methods: X-ray diffraction
-Differential inhibition of Morbillivirus and Henipavirus polymerases by ERDRP-0519 and structure-guided inhibitor optimization.
Cell, Vol. 189, Issue 13, Page 4094-4106.e13, Year 2026
Lu Xue / Jiacheng Gui / Shenghua Gao / Xiaoxiao Gao / Tiancai Chang / Hainei Pan / Jielin Tang / Mingxia Zhang / Zimu Li / Binqian Zou ...Lu Xue / Jiacheng Gui / Shenghua Gao / Xiaoxiao Gao / Tiancai Chang / Hainei Pan / Jielin Tang / Mingxia Zhang / Zimu Li / Binqian Zou / Heyu Zhao / Longyu Wang / Mei Li / Lijun Rong / Richard K Plemper / Xinwen Chen / Jun He / Rongjuan Pei / Peng Zhan / Xiaoli Xiong
Methods: EM (single particle)
-Pi-pi sandwich guided design of a de novo doxorubicin-binding protein
To Be Published,
Ouchida, S. / Gou, X. / Horst, M. / Bakanas, I. / Ashworth, A. / DeGrado, W.F.
Methods: X-ray diffraction
-Electron tomogram of the postmitotic nuclear envelope following acute Nup62 depletion
To Be Published,
Zhang W / Ellenberg J
Methods: EM (tomography)
-OspC from Borrelia Garinii
To Be Published,
Timofeev, V.I. / Nikolaeva, A.Y. / Lazarenko, V.A. / Dorovatovskiy, P.V. / Vlaskina, A.V. / Petrenko, D.E. / Agapova, Y.K. / Marchenkova, M.A. / Rakitina, T.V.
Methods: X-ray diffraction
-Crystal Structure of De Novo Protein Inhibitor of eEF2K
To Be Published,
Klupt, K.A. / Belrose, E.G. / Jia, Z.
Methods: X-ray diffraction
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