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-Structure paper
| Title | Transgenic Mouse-Derived Human Monoclonal Antibodies Targeting EBV gp350 and gp42 Provide Basis for Therapeutic Development |
|---|---|
| Journal, issue, pages | To Be Published |
| Publish date | Jul 3, 2025 (structure data deposition date) |
Authors | Chan CB / Lang K / Davis AR / Wan YH / Aldridge NT / Kher G / Scharffenberger SC / Hardy SR / Iureniev R / Giltiay NV ...Chan CB / Lang K / Davis AR / Wan YH / Aldridge NT / Kher G / Scharffenberger SC / Hardy SR / Iureniev R / Giltiay NV / Edwards KR / Radtke S / Kiem HP / Pancera M / McGuire A |
External links | Search PubMed |
| Methods | EM (single particle) / X-ray diffraction |
| Resolution | 3.93 - 9.86 Å |
| Structure data | ![]() EMDB-71585: Negative stain EM map of EBV glycoprotein gH/gL in complex with glycoprotein gp42 and FAB ATX-42-1.1 open conformation ![]() EMDB-71586: Negative stain EM map of EBV glycoprotein gH/gL in complex with glycoprotein gp42 and FAB ATX-42-2 Open conformation ![]() PDB-9pf9: |
| Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-HOH: |
| Source |
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Keywords | IMMUNE SYSTEM / Viral protein / Complex / Antibody / EBV |
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human gammaherpesvirus 4 (Epstein-Barr virus)
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