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TitleRapid acquisition of HIV-1 neutralization breadth in a rhesus V2 apex germline antibody mouse model with a single bolus priming immunization
Journal, issue, pagesTo Be Published
Publish dateMay 15, 2025 (structure data deposition date)
AuthorsAmrit G / Roark RS / Kwong PD / Batista FD
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.1 - 3.8 Å
Structure data

70663

9oog

EMDB-70663, PDB-9oog:
Cryo-EM structure of vaccine-elicited antibody T3_NB_G05 in complex with HIV Env trimer Q23-APEX-GT1.N187S
Method: EM (single particle) / Resolution: 3.1 Å

70664

9ook

EMDB-70664, PDB-9ook:
Cryo-EM structure of vaccine-elicited antibody T3_QB_G12 in complex with HIV Env trimer Q23-APEX-GT1
Method: EM (single particle) / Resolution: 3.8 Å

70666

9oom

EMDB-70666, PDB-9oom:
Cryo-EM structure of vaccine-elicited antibody T6_P_H03 in complex with HIV Env trimer Q23-APEX-GT1
Method: EM (single particle) / Resolution: 3.5 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • Macaca mulatta (Rhesus monkey)
  • mus musculus (house mouse)
  • homo sapiens (human)
  • Human immunodeficiency virus 1
  • human immunodeficiency virus type 1
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / immune complex / neutralizing antibody / V2 apex / mouse model / VIRAL PROTEIN / VIRAL PROTEIN-IMMUNE SYSTEM complex

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