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TitleArchitecture and function of holocentric CENP-A-independent inner kinetochores.
Journal, issue, pagesSci Adv, Vol. 12, Page eaeb5817, Year 2026
Publish dateMay 10, 2025
AuthorsYu, C. / Sankaranarayanan, S.R. / Cornilleau, G. / Howes, A.C. / Azumaya, C.M. / Day, E.S. / Zilberleyb, I. / Brillantes, B. / Cheung, T.K. / Dec, L. ...Yu, C. / Sankaranarayanan, S.R. / Cornilleau, G. / Howes, A.C. / Azumaya, C.M. / Day, E.S. / Zilberleyb, I. / Brillantes, B. / Cheung, T.K. / Dec, L. / Loew, D. / Tran, P. / Rose, C.M. / Drinnenberg, I.A. / Ciferri, C. / Yatskevich, S.
External linksSci Adv / PubMed:42319948
MethodsEM (single particle)
Resolution2.83 - 4.5 Å
Structure data

70558

9okb

EMDB-70558, PDB-9okb:
Structure of the dimeric Bombyx mori CCAN bound to DNA
Method: EM (single particle) / Resolution: 4.5 Å

70560

9okd

EMDB-70560, PDB-9okd:
Structure of the monomeric Bombyx mori CCAN bound to linear DNA
Method: EM (single particle) / Resolution: 2.83 Å

70561
EMDB Unreleased entry

9oke

EMDB-70561, PDB-9oke:
Structure of the Bombyx mori bmCENP-HIKM-LN-T-OP complex without the CS module
Method: EM (single particle) / Resolution: 3.24 Å

70567
EMDB Unreleased entry

9okk

EMDB-70567, PDB-9okk:
Bombyx mori bmCENP-LN-HIKM sub-complex structure
Method: EM (single particle) / Resolution: 3.23 Å

70568

9okl

EMDB-70568, PDB-9okl:
Structure of the Bombyx mori apo-bmCCAN
Method: EM (single particle) / Resolution: 3.0 Å

Chemicals

ChemComp-ZN:
Unknown entry

Source
  • bombyx mori (domestic silkworm)
  • synthetic construct (others)
  • spodoptera frugiperda (fall armyworm)
KeywordsDNA BINDING PROTEIN/DNA / CCAN / complex / protein-DNA / segregation / DNA BINDING PROTEIN / DNA BINDING PROTEIN-DNA complex / CELL CYCLE / DNA-protein / kinetochore

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