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TitleStructural basis for substrate recognition and inhibition of human glucose 6-phosphate transporter SLC37A4
Journal, issue, pagesTo Be Published
Publish dateDec 21, 2025 (structure data deposition date)
AuthorsWei X
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.8 - 3.3 Å
Structure data

67846

21np

EMDB-67846, PDB-21np:
Structure of human SLC37A4 bound to chlorogenic acid in a lipid nanodisc
Method: EM (single particle) / Resolution: 3.3 Å

67869

21or

EMDB-67869, PDB-21or:
Structure of human SLC37A4 bound to G6P
Method: EM (single particle) / Resolution: 2.8 Å

Chemicals

PDB-1eg7:
THE CRYSTAL STRUCTURE OF FORMYLTETRAHYDROFOLATE SYNTHETASE FROM MOORELLA THERMOACETICA

ChemComp-BG6:
6-O-phosphono-beta-D-glucopyranose

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / transporter

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