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TitleMolecular Mechanism of Ziresovir Targeting the Fusion Glycoprotein of Respiratory Syncytial Virus
Journal, issue, pagesTo Be Published
Publish dateAug 19, 2025 (structure data deposition date)
AuthorsZhang W / Yan MR / Zou JJ / Peng W
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.27 Å
Structure data

65894

9wdp

EMDB-65894, PDB-9wdp:
Cyro-EM structure of prefusion RSV fusion glycoprotein in complex with Ziresovir and motavizumab Fab
Method: EM (single particle) / Resolution: 3.27 Å

Chemicals

PDB-1ev1:
ECHOVIRUS 1

Source
  • human respiratory syncytial virus a2
  • tequatrovirus t4
  • mus musculus (house mouse)
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / Inhibitor / Complex / VIRAL PROTEIN-IMMUNE SYSTEM complex

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