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Structure paper

TitlePassive aberrant currents are induced by all Na pump variants causing hypomagnesemia
Journal, issue, pagesTo Be Published
Publish dateAug 12, 2025 (structure data deposition date)
AuthorsArtigas P / Abe K
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.39 - 2.86 Å
Structure data

65820

9waj

EMDB-65820, PDB-9waj:
Cryo-EM structure of a human sodium pump wildtype in ouabain-bound E2P state
Method: EM (single particle) / Resolution: 2.39 Å

65821

9wak

EMDB-65821, PDB-9wak:
Cryo-EM structure of a human sodium pump W931R mutant in ouabain-bound E2P state
Method: EM (single particle) / Resolution: 2.86 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-OBN:
OUABAIN

ChemComp-HOH:
WATER

ChemComp-CLR:
CHOLESTEROL

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / P-type ATPase / Na+ / K+ / ATPase / Na/K-ATPase / cation pump / transporter

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