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TitleStructure of mammalian RNA polymerase II stalled by a cisplatin-induced inter-strand crosslink lesion at the +2 position.
Journal, issue, pagesTo Be Published
Publish dateAug 8, 2025 (structure data deposition date)
AuthorsXu J / Zhu L
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.04 Å
Structure data

65750

9w8s

EMDB-65750, PDB-9w8s:
Structure of mammalian RNA polymerase II stalled by a cisplatin-induced inter-strand crosslink lesion at the +2 position.
Method: EM (single particle) / Resolution: 3.04 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CPT:
Cisplatin / medication*YM

ChemComp-MG:
Unknown entry

Source
  • sus scrofa (pig)
  • synthetic construct (others)
KeywordsTRANSCRIPTION / RNA polymerase II / cisplatin / inter-strand crosslink / transcription-coupled repair

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