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-Structure paper
| Title | Structural basis for chaperone-guided RISC assembly |
|---|---|
| Journal, issue, pages | To Be Published |
| Publish date | Aug 1, 2025 (structure data deposition date) |
Authors | Jeong M-S / Lee Y-Y / Lee H / Lee J-H / Lee D / Kim VN / Roh S-H |
External links | Search PubMed |
| Methods | EM (single particle) |
| Resolution | 2.63 - 3.17 Å |
| Structure data | ![]() EMDB-65658: AGO2-focused map of Hsp90-p23-AGO2 ![]() EMDB-65659: Focused map of Hsp90-p23 and lumen from Hsp90-p23-AGO2-miRNA duplex ![]() EMDB-65660: Focused map of AGO2 N-domain from Hsp90-p23-AGO2-miRNA duplex ![]() EMDB-65661: Focused map of AGO2 MID/PIWI domain from Hsp90-p23-AGO2-miRNA duplex ![]() EMDB-65662: Consensus map of Hsp90-p23-AGO2-miRNA duplex EMDB-65663, PDB-9w5i: ![]() EMDB-69544: Consensus map of Hsp90-p23-AGO2 |
| Chemicals | ![]() ChemComp-ATP: ![]() ChemComp-MG: |
| Source |
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Keywords | CHAPERONE / Hsp90 / p23 / Argonaute / miRNA / AGO2 / co-chaperone |
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homo sapiens (human)
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