Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Human ribosome interactions reframe neomycin toxicity
Journal, issue, pages	To Be Published
Publish date	Jul 19, 2025 (structure data deposition date)
Authors	Zhang X / Zhu L / Jia C / Wu K / Bai Y / Sun S / Zhang Z / Guo L / Hou X / Wu M ...Zhang X / Zhu L / Jia C / Wu K / Bai Y / Sun S / Zhang Z / Guo L / Hou X / Wu M / Amunts A / Li W
External links	Search PubMed
Methods	EM (single particle)
Resolution	2.51 - 3.4 Å
Structure data	EMDB Unreleased entry EMDB-65411: Human cytosolic ribosome isolated from 1mM neomycin treated cells, class non rotated state with P/P-site and E/E-site tRNAs Method: EM (single particle) / Resolution: 2.8 Å EMDB Unreleased entry EMDB-65412: Human cytosolic ribosome in complex with neomycin, class partially rotated state with E/E-site tRNAs, SERBP1 and eEF2 Method: EM (single particle) / Resolution: 3.0 Å EMDB Unreleased entry EMDB-65413: Human cytosolic ribosome isolated from 1mM neomycin treated cells, class partially rotated state with E/E-site tRNAs, eEF2 and SERBP1 Method: EM (single particle) / Resolution: 3.0 Å EMDB Unreleased entry EMDB-65414: Human cytosolic ribosome isolated from 1mM neomycin treated cells, class rotated state with A/A-site and P/E-site tRNAs Method: EM (single particle) / Resolution: 3.4 Å EMDB Unreleased entry EMDB-65415: Human cytosolic ribosome isolated from 1mM neomycin treated cells, class rotated state with A/P-site and P/E-site tRNAs Method: EM (single particle) / Resolution: 2.54 Å EMDB Unreleased entry EMDB-65416: Human cytosolic ribosome isolated from 3mM neomycin treated cells, class non rotated state with P/P-site and E/E-site tRNAs Method: EM (single particle) / Resolution: 2.93 Å EMDB Unreleased entry EMDB-65417: Human cytosolic ribosome isolated from 3mM antibiotic neomycin treated cells, class partially rotated state with E/E-site tRNAs, eEF2 and SERBP1 Method: EM (single particle) / Resolution: 3.14 Å EMDB Unreleased entry EMDB-65418: Human cytosolic ribosome isolated from 3mM neomycin treated cells, class rotated state with A/P-site and P/E-site tRNAs Method: EM (single particle) / Resolution: 2.82 Å EMDB Unreleased entry EMDB-65419: Human cytosolic ribosome in complex with neomycin, class non rotated state with P/P-site and E/E-site tRNAs Method: EM (single particle) / Resolution: 2.7 Å EMDB Unreleased entry EMDB-65420: Large subunit of human mitoribosome isolated from 1mM neomycin treated cells Method: EM (single particle) / Resolution: 3.1 Å EMDB Unreleased entry EMDB-65421: Human mitoribosome isolated from 1mM neomycin treated cells, class non rotated state with P/P-site and E/E-site tRNAs Method: EM (single particle) / Resolution: 3.4 Å EMDB Unreleased entry EMDB-65422: Human mitoribosome isolated from 1mM neomycin treated cells, class non rotated state with A/A-site, P/P-site and E/E-site tRNAs Method: EM (single particle) / Resolution: 2.84 Å EMDB Unreleased entry EMDB-65423: Human mitoribosome isolated from 1mM neomycin treated cells, class partially rotated state with A/A-site and P/P-site tRNAs Method: EM (single particle) / Resolution: 2.9 Å EMDB Unreleased entry EMDB-65424: Human mitoribosome isolated from 1mM neomycin treated cells, class partially rotated state with A/P-site and P/E-site tRNAs Method: EM (single particle) / Resolution: 3.1 Å EMDB Unreleased entry EMDB-65425: Human mitoribosome isolated from 1mM neomycin treated cells, class rotated state with P/E-site tRNAs Method: EM (single particle) / Resolution: 3.0 Å EMDB Unreleased entry EMDB-65426: Human mitoribosome in complex with neomycin, class non rotated state with A/A-site, P/P-site and E/E-site tRNAs Method: EM (single particle) / Resolution: 3.0 Å EMDB Unreleased entry EMDB-65427: Human mitoribosome in complex with neomycin, class partially rotated state with A/A-site, P/P-site and E/E-site tRNAs Method: EM (single particle) / Resolution: 3.3 Å EMDB Unreleased entry EMDB-65428: Human mitoribosome in complex with neomycin, class partially rotated state with A/P-site and P/E-site tRNAs Method: EM (single particle) / Resolution: 3.2 Å EMDB Unreleased entry EMDB-65429: Human mitoribosome in complex with neomycin, class rotated state Method: EM (single particle) / Resolution: 3.2 Å EMDB Unreleased entry EMDB-65431: Human mitoribosome in complex with neomycin, class rotated state with A/P-site and P/E-site tRNAs Method: EM (single particle) / Resolution: 3.3 Å 65433 EMDB Unreleased entry 9vxm EMDB-65433: Cryo-EM map of the human mitoribosome in a non-rotated state, with multiple neomycin molecules bound, featuring A/A-site and P/P-site tRNAs PDB-9vxm: Human mitoribosome in a non-rotated state, with multiple neomycin molecules bound, featuring A/A-site and P/P-site tRNAs Method: EM (single particle) / Resolution: 2.9 Å 65434 EMDB Unreleased entry 9vxn EMDB-65434: Cryo-EM map of the human cytosolic ribosome in a rotated state, with multiple neomycin molecules bound, featuring A/P-site and P/E-site tRNAs PDB-9vxn: Human cytosolic ribosome in a rotated state, with multiple neomycin molecules bound, featuring A/P-site and P/E-site tRNAs Method: EM (single particle) / Resolution: 2.51 Å
Chemicals	ChemComp-ZN: Unknown entry ChemComp-K: Unknown entry ChemComp-SPD: SPERMIDINE ChemComp-PUT: 1,4-DIAMINOBUTANE ChemComp-MG: Unknown entry ChemComp-NMY: NEOMYCIN / antibioticYM ChemComp-VAL: VALINE ChemComp-FES: FE2/S2 (INORGANIC) CLUSTER ChemComp-NAD: NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NADYM ChemComp-SPM: SPERMINE ChemComp-ATP: ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying moleculeYM ChemComp-GDP: GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying moleculeYM ChemComp-IAS: BETA-L-ASPARTIC ACID
Source	homo sapiens (human)
Keywords	RIBOSOME / mitoribosome / neomycin / cytosolic ribosome