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TitleIdentification of An Anti-cancer Pre-clinical Candidate as A Potent Inhibitor of RNA Splicing
Journal, issue, pagesTo Be Published
Publish dateJul 13, 2025 (structure data deposition date)
AuthorsWang L / Yang Y / Zheng Z / Zhan X / Shi Y
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.7 Å
Structure data

65363

9vuh

EMDB-65363, PDB-9vuh:
CDK11B ternary complex bound to AT7519
Method: EM (single particle) / Resolution: 2.7 Å

Chemicals

ChemComp-LZE:
4-{[(2,6-dichlorophenyl)carbonyl]amino}-N-piperidin-4-yl-1H-pyrazole-3-carboxamide

Source
  • homo sapiens (human)
KeywordsSPLICING / AT7519 / CDK11 / Cyclin L1 / SAP30BP

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