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Structure paper

TitleDNA-histone cross-link locks the nucleosome structure and disrupts its recognition and processing.
Journal, issue, pagesProtein Cell, Vol. 17, Issue 5, Page 476-482, Year 2026
Publish dateMay 1, 2026
AuthorsXiajing Shan / Gaoyuan Ji / Jiahui Li / Mengtian Ren / Jingke Ma / Yifei Zhou / Haitao Li / Chuanzheng Zhou /
External linksProtein Cell / PubMed:41206067 / PubMed Central
MethodsEM (single particle)
Resolution3.24 Å
Structure data

64640

9uz7

EMDB-64640, PDB-9uz7:
Cryo-EM structure of the nucleosome core particle with site-specific DNA-histone crosslinking
Method: EM (single particle) / Resolution: 3.24 Å

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN/DNA / Histone / Nucleosome / DNA BINDING PROTEIN / DNA BINDING PROTEIN-DNA complex

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