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Structure paper

TitleStructural and functional insights into HBx-Smc6 targeting for HBV inhibition.
Journal, issue, pagesCell Res, Year 2026
Publish dateApr 16, 2026
AuthorsTong Cheng / Jinhong Zhou / Wenjun Huang / Lili Du / Pengyu He / Renzheng Yang / Yan Gao / Menghan Hao / Kongying Hu / Jieliang Chen / Hongxia Wang / Zihe Rao / Zhenghong Yuan / Lanfeng Wang /
External linksCell Res / PubMed:41991645
MethodsEM (single particle)
Resolution3.12 - 7.32 Å
Structure data

63446

9lwi

EMDB-63446, PDB-9lwi:
The head region of HBx-Smc5/6 ubiquitination complex
Method: EM (single particle) / Resolution: 3.12 Å

63447

9lwj

EMDB-63447, PDB-9lwj:
The head-arm region of HBx-Smc5/6 ubiquitination complex
Method: EM (single particle) / Resolution: 7.19 Å

63448

9lwk

EMDB-63448, PDB-9lwk:
The hinge-arm region of HBx-Smc5/6 ubiquitination complex
Method: EM (single particle) / Resolution: 7.32 Å

63449

9lwl

EMDB-63449, PDB-9lwl:
HBx-Smc5/6 ubiquitination complex
Method: EM (single particle) / Resolution: 7.25 Å

Chemicals

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
  • hepatitis b virus
KeywordsANTIVIRAL PROTEIN / HBx / Smc5/6 / Cul4A-RBx / HBV / DNA BINDING PROTEIN

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