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Structure paper

TitleGPCR exoframe modulators
Journal, issue, pagesTo Be Published
Publish dateJan 17, 2025 (structure data deposition date)
AuthorsCheng S / Guo J / Zhou Y / Zhang Y
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.0 Å
Structure data

63203

9lli

EMDB-63203, PDB-9lli:
Cryo-EM structure of D1R in complex with de novo designed GEM targeting TM1/2/4 and GEM targeting TM3/4/5, and negative allosteric GEM targeting TM5/6/7
Method: EM (single particle) / Resolution: 3.0 Å

Chemicals

PDB-1ekl:
TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 E35K

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsMEMBRANE PROTEIN / GPCR / GEM / GPCR exoframe modulator / D1R

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