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Structure paper

TitleStructure of human PRC2 with SAH and H3K27me3 peptide
Journal, issue, pagesTo Be Published
Publish dateNov 20, 2024 (structure data deposition date)
AuthorsGao H / Cao T / Liu Y / Liu D / Yu H / Qi W
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.07 - 3.59 Å
Structure data

62474

9kof

EMDB-62474, PDB-9kof:
Structure of human PRC2 with SAH and H3K27me3 peptide
Method: EM (single particle) / Resolution: 3.07 Å

62475

9kog

EMDB-62475, PDB-9kog:
Structure of human PRC2 with C36 compound
Method: EM (single particle) / Resolution: 3.59 Å

62476

9koh

EMDB-62476, PDB-9koh:
Structure of human PRC2-SAH-H3K27me3-C36
Method: EM (single particle) / Resolution: 3.1 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

PDB-1egc:
STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE COMPLEXED WITH OCTANOYL-COA

Source
  • homo sapiens (human)
KeywordsGENE REGULATION / H3K27 methyltransferase; PRC2 / H3K27 methyltransferase; PRC2;inhibitor / H3K27 methyltransferase; PRC2; inhibitor

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