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| Title | Structure and function of the EDEM:PDI ERAD checkpoint complex |
|---|---|
| Journal, issue, pages | Biorxiv, Year 2025 |
| Publish date | Apr 7, 2026 (structure data deposition date) |
Authors | Hitchman CJ / Lia A / Chiritoiu GN / Munteanu CVA / Ortigosa JR / Ghenea S / Savva C / Wada I / De Benedictis M / Tax G ...Hitchman CJ / Lia A / Chiritoiu GN / Munteanu CVA / Ortigosa JR / Ghenea S / Savva C / Wada I / De Benedictis M / Tax G / Bayo Y / Crescioli I / Alonzi DL / Quigley A / Modenutti CP / Petrescu SM / Santino A / Gooptu B / Hosokawa N / Roversi P |
External links | Biorxiv / Search PubMed |
| Methods | EM (single particle) |
| Resolution | 3.46 Å |
| Structure data | EMDB-57361, PDB-29te: |
| Chemicals | ![]() ChemComp-MAN: ![]() ChemComp-CA: ![]() ChemComp-KIF: ![]() ChemComp-NAG: ![]() ChemComp-BMA: |
| Source |
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Keywords | HYDROLASE / mannosidase / disulfide isomerase / glycoprotein degradation / erad / misfolding / OXIDOREDUCTASE / serpin / Alpha1 antitrypsin / null Hong Kong / A1AT |
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