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Structure paper

Titlehuman 48S PIC with Kozak_1 mRNA
Journal, issue, pagesTo Be Published
Publish dateMar 3, 2026 (structure data deposition date)
Authorsvon Loeffelholz O / Barchet C / Holvec S / Abou Ramadan A / Maglott-Roth A / de Silva SNT / Hazemann I / Klaholz B
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.78 - 3.84 Å
Structure data

57009

28zx

EMDB-57009, PDB-28zx:
human 48S PIC with mRNA (Kozak_1)
Method: EM (single particle) / Resolution: 2.8 Å

57010

28zy

EMDB-57010, PDB-28zy:
human 48S PIC with mRNA (Kozak_2)
Method: EM (single particle) / Resolution: 3.0 Å

EMDB-57013: focused refined map; human eIF3 in 48S PIC on Kozak mRNA (Kozak_2)
Method: EM (single particle) / Resolution: 3.8 Å

EMDB-57014: focused refined map; 40S head with TC from human 48S PIC on Kozak mRNA (Kozak_2)
Method: EM (single particle) / Resolution: 3.0 Å

EMDB-57016: consensus map; human 48S PIC on Kozak mRNA (Kozak_2)
Method: EM (single particle) / Resolution: 3.0 Å

EMDB-57017: focused refined map; map for 40S body from human 48S PIC on Kozak mRNA (Kozak_1)
Method: EM (single particle) / Resolution: 2.78 Å

EMDB-57018: focused refined map; 40S head with TC from human 48S PIC on Kozak mRNA (Kozak_1)
Method: EM (single particle) / Resolution: 2.85 Å

EMDB-57019: focused refined map; human eIF3 in 48S PIC on Kozak mRNA (Kozak_1)
Method: EM (single particle) / Resolution: 3.84 Å

EMDB-57020: consensus map; human 48S PIC on Kozak mRNA (Kozak_1)
Method: EM (single particle) / Resolution: 3.0 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-GNP:
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / GppNHp, GMPPNP, energy-carrying molecule analogue*YM

ChemComp-MET:
METHIONINE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • homo (humans)
KeywordsRIBOSOME / translation initiation / 48S PIC / human

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