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Structure paper

TitleSaskemycin, a potent antimycobacterial agent targeting a unique site in the ribosome
Journal, issue, pagesTo Be Published
Publish dateJan 30, 2026 (structure data deposition date)
AuthorsCook MA / Xu M / Wang W / Rao VN / Schaenzer AJ / Wang L / Yarlagadda V / Guitor AK / Ejim L / Wright G ...Cook MA / Xu M / Wang W / Rao VN / Schaenzer AJ / Wang L / Yarlagadda V / Guitor AK / Ejim L / Wright G / Golas AJ / Nietupski RM / Fitzgerald M / Hung DT / Sahile H / Av-Gay Y / Lin S / Dhar N / Travin D / Klepacki D / Vazquez-Laslop N / Mankin A / Morici M / Corazza M / Safdari HA / Berger M / Wilson DN
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.3 - 3.42 Å
Structure data

EMDB-56520: Cryo-EM map of SKM-70S complex State 2 (Accommodating A-tRNA)
Method: EM (single particle) / Resolution: 2.3 Å

EMDB-56525: Cryo-EM map of SKM-70S complex State 4 (Accommodated A-tRNA)
Method: EM (single particle) / Resolution: 2.3 Å

EMDB-56530: Cryo-EM map of SKM-70S complex State 6 (Empty, canonical)
Method: EM (single particle) / Resolution: 2.75 Å

EMDB-57122: Cryo-EM map of SKM-70S complex State 7 (Empty, rotated)
Method: EM (single particle) / Resolution: 3.42 Å

Source
  • Escherichia coli B (bacteria)

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