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TitleDiscovery of Membrane Channel Modulators via DNA-Encoded Library Screening Using Native-Like Membrane Protein Nanoparticles
Journal, issue, pagesBiorxiv, Year 2026
Publish dateJan 21, 2026 (structure data deposition date)
AuthorsReddavide FV / Toft-Bertelsen TL / Drulyte I / Gutgsell AR / Nguyen D / Bonetti S / Vafia K / Tournillon AS / Heiden S / Grosser D ...Reddavide FV / Toft-Bertelsen TL / Drulyte I / Gutgsell AR / Nguyen D / Bonetti S / Vafia K / Tournillon AS / Heiden S / Grosser D / Iric K / Diez V / MacAulay N / Geschwindner S / Thompson M / Frauenfeld J / Loving R
External linksBiorxiv / Search PubMed
MethodsEM (single particle)
Resolution4.5 Å
Structure data

EMDB-56448: Cryo-EM structure of mouse Pannexin 1 in complex with a ligand
Method: EM (single particle) / Resolution: 4.5 Å

Source
  • Mus musculus (house mouse)

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