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-Structure paper
| Title | The plasma protease inhibitor ITIH4 forms oligomeric complexes and senses broader, proteolytic activity |
|---|---|
| Journal, issue, pages | To Be Published |
| Publish date | Jan 15, 2026 (structure data deposition date) |
Authors | Joergensen MH / Andersen GR |
External links | Search PubMed |
| Methods | EM (single particle) |
| Resolution | 3.02 - 3.79 Å |
| Structure data | EMDB-56397, PDB-9txi: EMDB-56398, PDB-9txj: EMDB-56399, PDB-9txk: ![]() EMDB-56400: Consensus structure of ITIH4N:MASP-1cf:12A12 F(ab) 2:1:2 complex ![]() EMDB-56401: ITIH4N:MASP-1cf:12A12 F(ab) 2:1:2 complex (ITIH4N #1 Focus) ![]() EMDB-56402: ITIH4N:MASP-1cf:12A12 F(ab) 2:1:2 complex (ITIH4N #2 Focus) ![]() EMDB-56403: Cryo-EM structure of ITIH4N:PKK:12A12 F(ab) 2:1:2 complex EMDB-56404, PDB-9txl: |
| Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-MG: ![]() ChemComp-HOH: |
| Source |
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Keywords | IMMUNE SYSTEM / Protease inhibitor / plasma protein / complement / coagulation / contact cascade |
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homo sapiens (human)
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