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| Title | Cryo-EM structure of human VPS34-CI in complex with GABARAP |
|---|---|
| Journal, issue, pages | To Be Published |
| Publish date | Jan 13, 2026 (structure data deposition date) |
Authors | Dessus AN / Williams RL |
External links | Search PubMed |
| Methods | EM (single particle) |
| Resolution | 3.28 - 4.01 Å |
| Structure data | ![]() EMDB-56343: Cryo-EM structure of human VPS34-CI in complex with GABARAP - alternative conformation, local refinement on BECLIN1 and ATG14L C-terminal domains. ![]() EMDB-56345: Cryo-EM structure of human VPS34-CI in complex with GABARAP - alternative conformation, consensus map ![]() EMDB-56346: Cryo-EM structure of human VPS34-CI in complex with GABARAP, consensus map ![]() EMDB-56347: Cryo-EM structure of human VPS34-CI in complex with GABARAP, local refinement on VPS34 and VPS15 kinase domains. ![]() EMDB-56348: Cryo-EM structure of human VPS34-CI in complex with GABARAP, local refinement on the core of VPS34-CI. ![]() EMDB-56350: Cryo-EM structure of human VPS34-CI in complex with GABARAP, local refinement on VPS15 helical solenoid, and BECLIN1 and ATG14L N-terminal domains. ![]() EMDB-56351: Cryo-EM structure of human VPS34-CI in complex with GABARAP, local refinement on GABARAP. ![]() EMDB-56353: Cryo-EM structure of human VPS34-CI in complex with GABARAP, local refinement on BECLIN1 and ATG14L C-terminal domains. EMDB-56357: Cryo-EM structure of human VPS34-CI in complex with GABARAP, composite map EMDB-56358: Cryo-EM structure of human VPS34-CI in complex with GABARAP - alternative conformation, composite map |
| Chemicals | ![]() ChemComp-MYR: ![]() ChemComp-GDP: ![]() ChemComp-MG: ![]() ChemComp-ZN: |
| Source |
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Keywords | LIPID BINDING PROTEIN / Lipid kinase / Complex / Autophagy |
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homo sapiens (human)
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