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-Structure paper
| Title | High-resolution cryo-EM structure of integrin aIIbb3 in complex with a disease-causing maternal HPA-1a antibody that blocks integrin activation |
|---|---|
| Journal, issue, pages | To Be Published |
| Publish date | Nov 22, 2025 (structure data deposition date) |
Authors | de Pereda JM / Stam W / Gragera M / van der Meer F / Chichon FJ / Zarkadas E / van der Schoot E / Vidarsson G / Takagi J / Margadant C |
External links | Search PubMed |
| Methods | EM (single particle) |
| Resolution | 2.64 Å |
| Structure data | EMDB-55800, PDB-9td2: |
| Chemicals | ![]() ChemComp-CA: ![]() ChemComp-NAG: ![]() ChemComp-MG: ![]() ChemComp-HOH: |
| Source |
|
Keywords | CELL ADHESION / Human Platelet Antigen / FNAIT / alloantibody / cryo-EM |
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homo sapiens (human)
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