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TitleActivation intermediate of ALC1/CHD1L bound to a PARylated nucleosome
Journal, issue, pagesBiorxiv, Year 2025
Publish dateNov 2, 2025 (structure data deposition date)
AuthorsBridges HR / Bacic L / Deindl S / Gaullier G
External linksBiorxiv / Search PubMed
MethodsEM (single particle)
Resolution2.96 - 6.6 Å
Structure data

55533

9t4v

EMDB-55533, PDB-9t4v:
Activation intermediate of ALC1/CHD1L bound to a PARylated nucleosome
Method: EM (single particle) / Resolution: 6.6 Å

EMDB-55534: Activation intermediate of ALC1/CHD1L bound to a PARylated nucleosome - regulatory linker segment resolved
Method: EM (single particle) / Resolution: 2.96 Å

Source
  • xenopus laevis (African clawed frog)
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN / ALC1 / CHD1L / chromatin remodeler / DNA damage response / nucleosome / poly(ADP-ribose)

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