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Structure paper

TitleStructures of asymmetric particles of TBEV provide insight into flavivirus assembly and maturation
Journal, issue, pagesTo Be Published
Publish dateOct 7, 2025 (structure data deposition date)
AuthorsFuzik T / Anastasina M / Pajtinka P / Domanska A / Pulkkinen LIA / Smerdova L / Nepovimova L / Formanova-Pokorna P / Strakova P / Novacek J ...Fuzik T / Anastasina M / Pajtinka P / Domanska A / Pulkkinen LIA / Smerdova L / Nepovimova L / Formanova-Pokorna P / Strakova P / Novacek J / Ruzek D / Vacha R / Butcher SJ / Plevka P
External linksSearch PubMed
MethodsEM (single particle) / EM (subtomogram averaging)
Resolution3.57 - 10.96 Å
Structure data

55311

9swk

EMDB-55311, PDB-9swk:
Immature TBEV envelope spike with interaction partners underneath - SPA
Method: EM (single particle) / Resolution: 3.57 Å

EMDB-55312: Immature TBEV envelope spike with interaction partners underneath - STA
Method: EM (subtomogram averaging) / Resolution: 4.24 Å

EMDB-55313: Asymmetric reconstruction of immature TBEV particle with 2 missing pentamers
Method: EM (single particle) / Resolution: 9.41 Å

EMDB-55314: Asymmetric reconstruction of immature TBEV particle with 2 irregularities
Method: EM (single particle) / Resolution: 10.25 Å

EMDB-55315: Asymmetric reconstruction of immature TBEV particle with altered 5-fold
Method: EM (single particle) / Resolution: 10.96 Å

EMDB-55316: Asymmetric reconstruction of TBEV virion
Method: EM (single particle) / Resolution: 5.1 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • tick-borne encephalitis virus
KeywordsVIRUS / tick borne encephalitis virus / envelope / flavivirus / spike / asymmetric / immature particle / SPA

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