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TitleE3 ligase mechanism of target-directed microRNA degradation
Journal, issue, pagesTo Be Published
Publish dateJul 10, 2025 (structure data deposition date)
AuthorsFarnung J / Slobodyanyuk E / Wang PY / Lin DH / Blodgett LA / Schulman BA / Bartel DP
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.1 Å
Structure data

EMDB-54351: Map C focused map of ZSWIM8-CUL3 complex bound to AGO2-miR-7-CYRANO
Method: EM (single particle) / Resolution: 3.1 Å

54352

9rwz

EMDB-54352: Map E Composite map of ZSWIM8-CUL3 complex bound to AGO2-miR-7-CYRANO
PDB-9rwz: ZSWIM8-CUL3 complex bound to AGO2-miR-7-CYRANO
Method: EM (single particle) / Resolution: 3.1 Å

Chemicals

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsLIGASE / miRNA / E3 Ligase

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