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TitleThe E3 ubiquitin ligase mechanism specifying target-directed microRNA degradation
Journal, issue, pagesTo Be Published
Publish dateJul 10, 2025 (structure data deposition date)
AuthorsFarnung J / Slobodyanyuk E / Wang PY / Lin DH / Blodgett LA / Schulman BA / Bartel DP
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.1 Å
Structure data

EMDB-54348: Map A ZSWIM8-CUL3 complex bound to AGO2-miR-7-CYRANO
Method: EM (single particle) / Resolution: 3.1 Å

EMDB-54349: Map B Locally refined interactions of ZSWIM8-CUL3 complex bound to AGO2-miR-7-CYRANO
Method: EM (single particle) / Resolution: 3.1 Å

EMDB-54350: Map D Locally refined map of ZSWIM8-CUL3 complex bound to AGO2-miR-7-CYRANO
Method: EM (single particle) / Resolution: 3.1 Å

Source
  • Homo sapiens (human)

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