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Structure paper

TitleCryoEM structure of human alpha1beta3gamma2L GABA(A)R in CL47a
Journal, issue, pagesTo Be Published
Publish dateJun 6, 2025 (structure data deposition date)
AuthorsKasaragod VB / Aricescu AR
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.0 Å
Structure data

53948

9rgd

EMDB-53948, PDB-9rgd:
CryoEM structure of human alpha1beta3gamma2L GABA(A)R in CL47a
Method: EM (single particle) / Resolution: 2.0 Å

Chemicals

ChemComp-D10:
DECANE

ChemComp-PT5:
[(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho / phospholipid*YM

ChemComp-R16:
HEXADECANE

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-PX2:
1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE

ChemComp-OLC:
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

ChemComp-PLM:
PALMITIC ACID

ChemComp-HEX:
HEXANE

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-PGW:
(1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl / phospholipid*YM

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / GABA / Neurotransmission / Inhibitory synapse

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