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TitleAI-guided prefusion stabilization of the human coronavirus OC43 spike protein enables universal Embecovirus antigen design
Journal, issue, pagesTo Be Published
Publish dateMay 13, 2025 (structure data deposition date)
AuthorsMelchers JM / Juraszek J / Hulswit RJG / van Overveld D / Le L / van Kuppeveld F / Hurdiss DL / Bosch BJ / Langedijk JPM / Bakkers MJG
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.76 Å
Structure data

53687

9r6t

EMDB-53687, PDB-9r6t:
Prefusion stabilized spike glycoprotein of equine coronavirus.
Method: EM (single particle) / Resolution: 2.76 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-8Z9:
Sapienic acid

Source
  • equine coronavirus
KeywordsVIRAL PROTEIN / fusion glycoprotein / membrane protein

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