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TitleAI-guided prefusion stabilization of the human coronavirus OC43 spike protein enables universal Embecovirus antigen design.
Journal, issue, pagesTo Be Published
Publish dateMay 13, 2025 (structure data deposition date)
AuthorsMelchers JM / Juraszek J / Hulswit RJG / van Overveld D / Le L / van Kuppeveld F / Hurdiss DL / Bosch BJ / Langedijk JPM / Bakkers MJG
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.1 Å
Structure data

53686

9r6s

EMDB-53686, PDB-9r6s:
Prefusion stabilized spike glycoprotein of human coronavirus OC43.
Method: EM (single particle) / Resolution: 3.1 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-8Z9:
Sapienic acid

Source
  • human coronavirus oc43
KeywordsVIRAL PROTEIN / fusion glycoprotein / membrane protein

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