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TitleDesign principles of a membrane-tethered ubiquitin ligase
Journal, issue, pagesMol Cell, Year 2026
Publish dateApr 4, 2025 (structure data deposition date)
AuthorsWilliams C / Nocka LM / Hedger G / Carrique L / Pusapati GV / Parashara P / Latorraca NR / Lartey D / Gao L / Pardon E ...Williams C / Nocka LM / Hedger G / Carrique L / Pusapati GV / Parashara P / Latorraca NR / Lartey D / Gao L / Pardon E / Milenkovic L / Chalk R / Steyaert J / Bazan F / Rouse SL / Marqusee S / Kong JH / Siebold C / Rohatgi R
External linksMol Cell / Search PubMed
MethodsEM (single particle)
Resolution2.74 - 3.33 Å
Structure data

EMDB-53321: Focused refinement of the MGRN1 ubiquitin ligase in complex with MEGF8, MOSMO and nanobody 270
Method: EM (single particle) / Resolution: 3.33 Å

EMDB-53322: Structure of the MMM ubiquitin ligase complex with nanobody 270 (Consensus map)
Method: EM (single particle) / Resolution: 2.74 Å

Source
  • Homo sapiens (human)
  • Lama glama (llama)

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