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TitleStructural basis of pro-inflammatory signaling via the IL-36 receptor mediated by IL-36g and IL-37
Journal, issue, pagesTo Be Published
Publish dateFeb 3, 2025 (structure data deposition date)
AuthorsAndries J / Toul M / Felix J / Clancy DM / Savvides SN
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.27 Å
Structure data

52665

9i7x

EMDB-52665, PDB-9i7x:
Cryo-EM structure of human IL-36gamma in complex with the IL-36R and IL-1RAcP ectodomains
Method: EM (single particle) / Resolution: 3.27 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / cytokine / receptor complex / inflammation / IL-1 family

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