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-Structure paper
| Title | Mutation of CDK7 at a conserved residue identifies a common mechanism of acquired resistance to CDK inhibitors in cancer |
|---|---|
| Journal, issue, pages | To Be Published |
| Publish date | Nov 27, 2024 (structure data deposition date) |
Authors | Lai C-F / Cushing VI / Bevan CL / Coombes RC / Greber BJ / Buluwela L / Ali S |
External links | Search PubMed |
| Methods | EM (single particle) |
| Resolution | 2.3 - 2.6 Å |
| Structure data | EMDB-52205, PDB-9hix: EMDB-52206, PDB-9hiy: EMDB-52207, PDB-9hj0: |
| Chemicals | ![]() ChemComp-V0G: ![]() ChemComp-HOH: ![]() ChemComp-AGS: ![]() ChemComp-MG: ![]() ChemComp-I74: |
| Source |
|
Keywords | TRANSFERASE / Kinase / complex / heterotrimer |
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homo sapiens (human)
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