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Structure paper

TitleR2TP-like complexes as quaternary chaperones. A comprehensive overview to understand the dynamic R2SP complex
Journal, issue, pagesTo Be Published
Publish dateNov 5, 2024 (structure data deposition date)
AuthorsSanto PE / Chago ME / Ley M / Gizardin-Fredon H / Chenuel T / Desligniere E / Plassart L / Paiva ACF / Sousa PMF / Bertrand E ...Santo PE / Chago ME / Ley M / Gizardin-Fredon H / Chenuel T / Desligniere E / Plassart L / Paiva ACF / Sousa PMF / Bertrand E / Charpentier B / Verheggen C / Quinternet M / Meyer P / Bandeiras TM / Cianferani S / Plisson-Chastang C / Manival X
External linksSearch PubMed
MethodsEM (single particle) / NMR (solution)
Resolution3.5 - 3.56 Å
Structure data

EMDB-52013, PDB-9hb4:
Hexameric RuvBL1/RuvBL2 bound to SPAG1 C-ter
Method: EM (single particle) / Resolution: 3.56 Å

EMDB-52336, PDB-9hpo:
Docedameric RuvBL1/RuvBL2
Method: EM (single particle) / Resolution: 3.5 Å

PDB-9hkr:
NMR structure of the C-terminal domain of the human SPAG1 protein
Method: SOLUTION NMR

Chemicals

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

Source
  • homo sapiens (human)
KeywordsCHAPERONE / AAA+ ATPase / R2SP Complex / R2TP-Like complex / PAQosome / Molecular Motor / R2SP / RUVBL1 / RUVBL2 / cilia / RuvBL1/RuvBL2 Dodecamer

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