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Structure paper

TitleEntire structure of ancestral alphaproteobacterial complex I reveals the mechanism to prevent its deactivation
Journal, issue, pagesTo Be Published
Publish dateJul 26, 2024 (structure data deposition date)
AuthorsYaikhomba M / Hirst J / Croll TI / Spikes TE
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.0 - 3.19 Å
Structure data

EMDB-51180: Consensus map of the alphaproteobacterial respiratory supercomplex CI1-CIII2-CIV2
Method: EM (single particle) / Resolution: 3.19 Å

51181

9gae

EMDB-51181, PDB-9gae:
Respiratory supercomplex CI1-CIII2-CIV2 from alphaproteobacterium
Method: EM (single particle) / Resolution: 3.0 Å

Chemicals

ChemComp-3PE:
1,2-Distearoyl-sn-glycerophosphoethanolamine / phospholipid*YM

ChemComp-PGT:
(1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE / phospholipid*YM

ChemComp-DU0:
2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-U10:
UBIQUINONE-10

ChemComp-PC1:
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE / phospholipid*YM

ChemComp-CA:
Unknown entry

ChemComp-FES:
FE2/S2 (INORGANIC) CLUSTER

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-3PH:
1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE

ChemComp-P5S:
O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine

ChemComp-T7X:
Phosphatidylinositol

ChemComp-ZN:
Unknown entry

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-HEC:
HEME C

ChemComp-CDL:
CARDIOLIPIN / phospholipid*YM

ChemComp-HEA:
HEME-A

ChemComp-CU:
COPPER (II) ION

ChemComp-MN:
Unknown entry

ChemComp-CUA:
DINUCLEAR COPPER ION

Source
  • paracoccus denitrificans pd1222 (bacteria)
KeywordsELECTRON TRANSPORT / Supercomplex / multi-subunit membrane protein complex / electron transport chain / native purification

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