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Structure paper

TitleStructural Diversity of Metabotropic Glutamate Receptor/Beta-Arrestin Coupling
Journal, issue, pagesTo Be Published, Vol. To Be Published
Publish dateFeb 10, 2025 (structure data deposition date)
AuthorsMarx DC / Gonzalex-Hernandez AJ / Huynh K / Strauss A / Rico C / Siepe D / Gallo PN / Lee J / Sharghi S / Arefin A ...Marx DC / Gonzalex-Hernandez AJ / Huynh K / Strauss A / Rico C / Siepe D / Gallo PN / Lee J / Sharghi S / Arefin A / Broichhagen J / Eliezer D / Kalocsay M / Khelashvilli G / Levitz J
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.76 - 2.97 Å
Structure data

49153

9n8y

EMDB-49153, PDB-9n8y:
Cryo EM Structure of Full Length mGluR8 Bound to Agonist L-AP4 and PAM VU6005649
Method: EM (single particle) / Resolution: 2.76 Å

49154

9n8z

EMDB-49154, PDB-9n8z:
Cryo EM Structure of Full Length mGluR8 Bound to Agonist L-AP4 and PAM VU6005649, class 2
Method: EM (single particle) / Resolution: 2.97 Å

Chemicals

ChemComp-E7P:
(2S)-2-amino-4-phosphonobutanoic acid / agonist*YM

PDB-1bwg:
DNA TRIPLEX WITH 5' AND 3' JUNCTIONS, NMR, 10 STRUCTURES

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / GPCR / metabotropic glutamate receptor / synaptic protein / signaling protein

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