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Structure paper

TitleIndividualized IG genotyping coupled with high throughput isolation of influenza HA-specific monoclonal antibodies
Journal, issue, pagesTo Be Published
Publish dateFeb 6, 2025 (structure data deposition date)
AuthorsFisher A / Corcoran M / Chernyshev M / Brouwer PJM / Gillespie R / Nicoletto A / Loeffler JR / Ferguson JA / Rodriguez AJ / Narang S ...Fisher A / Corcoran M / Chernyshev M / Brouwer PJM / Gillespie R / Nicoletto A / Loeffler JR / Ferguson JA / Rodriguez AJ / Narang S / Adori M / Angeletti D / van Gils M / Castro Dopico X / Kanekiyo M / Ward AB / Han J / Karllson Hedestam GB
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.97 - 3.18 Å
Structure data

49097

9n7q

EMDB-49097, PDB-9n7q:
H1 hemagglutinin (A/Michigan/45/2015) in complex with anchor-targeting Fab ST15
Method: EM (single particle) / Resolution: 3.18 Å

49098

9n7s

EMDB-49098, PDB-9n7s:
H1 hemagglutinin (A/California/04/2009) with E47K mutation in HA2 in complex with central stem-targeting Fab ST10
Method: EM (single particle) / Resolution: 2.97 Å

49099

9n7t

EMDB-49099, PDB-9n7t:
H5 hemagglutinin (A/Jiangsu/NJ210/2023) in complex with central stem-targeting Fab ST14
Method: EM (single particle) / Resolution: 3.01 Å

49100

9n7v

EMDB-49100, PDB-9n7v:
H1 hemagglutinin (A/Michigan/45/2015) in complex with anchor-targeting Fab ST4
Method: EM (single particle) / Resolution: 3.15 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
  • influenza a virus
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / influenza / hemagglutinin / H1 / monoclonal / complex / fab complex / viral fusion protein / VIRAL PROTEIN / VIRAL PROTEIN-IMMUNE SYSTEM complex / H5

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