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TitleA Novel Actinobacteria-Specific Ribosome Hibernation Factor in Mycobacterium tuberculosis
Journal, issue, pagesBiorxiv, Year 2024
Publish dateOct 21, 2024 (structure data deposition date)
AuthorsMajumdar S / Li Y / Manjari SR / Gamper HB / Hou YM / Banavali NK / Ojha AK / Agrawal RK
External linksBiorxiv / Search PubMed
MethodsEM (single particle)
Resolution2.39 - 3.34 Å
Structure data

47384

9e16

EMDB-47384, PDB-9e16:
Cryo-EM structure of the ribosome-tunnel occluding hibernation factor bound to the Mycobacterium tuberculosis C- 70S ribosome carrying an E-tRNA
Method: EM (single particle) / Resolution: 2.7 Å

47419

9e1s

EMDB-47419, PDB-9e1s:
Cryo-EM structure of the ribosome-tunnel occluding hibernation factor bound to the Mycobacterium tuberculosis C- 50S ribosomal subunit
Method: EM (single particle) / Resolution: 2.39 Å

47876

9ebb

EMDB-47876, PDB-9ebb:
Cryo-EM structure of the MPY and ribosome-tunnel occluding hibernation factors bound to the Mycobacterium tuberculosis C- 70S ribosome
Method: EM (single particle) / Resolution: 2.7 Å

47899

9ec3

EMDB-47899, PDB-9ec3:
Cryo-EM structure of the ribosome-tunnel occluding hibernation factor bound to the Mycobacterium tuberculosis C- 70S ribosome carrying fMet-tRNA(fMet) and deacylated tRNA at ribosome P and E sites.
Method: EM (single particle) / Resolution: 3.29 Å

EMDB-47909: Cryo-EM structure of the ribosome-tunnel occluding hibernation factor bound to Mycobacterium tuberculosis C- 70S ribosome
Method: EM (single particle) / Resolution: 2.78 Å

EMDB-47910: Cryo-EM structure of the Mycobacterium tuberculosis C- 70S ribosome bound to fMet-tRNA(fMet) and deacylated tRNA at ribosome P and E sites
Method: EM (single particle) / Resolution: 3.34 Å

Source
  • mycobacterium tuberculosis (bacteria)
  • escherichia coli (E. coli)
KeywordsRIBOSOME / hibernating ribosome / Mycobacterium tuberculosis / nascent peptide exit tunnel / 70S / hibernation factor / TRANSLATION / 50S / Mpy

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