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Structure paper

TitleATP decline delocalizes tau from microtubules
Journal, issue, pagesTo Be Published
Publish dateAug 21, 2024 (structure data deposition date)
AuthorsGrycova L / Humhalova T / Perez-Bertoldi JM / Peukes J / Hlubuckova D / Khuntsariya D / Krishnan A / Zdobinsky T / Dodokova A / Diez S ...Grycova L / Humhalova T / Perez-Bertoldi JM / Peukes J / Hlubuckova D / Khuntsariya D / Krishnan A / Zdobinsky T / Dodokova A / Diez S / Janke C / Barvik I / Libusova L / Nogales E / Braun M / Lansky Z
External linksSearch PubMed
MethodsEM (helical sym.)
Resolution2.94 Å
Structure data

46689

9da8

EMDB-46689, PDB-9da8:
Tau-Microtubule structure in the presence of ATP
Method: EM (helical sym.) / Resolution: 2.94 Å

Chemicals

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-TA1:
TAXOL / medication*YM

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

Source
  • sus scrofa (pig)
  • homo sapiens (human)
KeywordsPROTEIN BINDING / Tau / Tubulin / ATP / Neurodegeneration

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