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Structure paper

TitleCryo-EM structures of human alpha1B/betaI+betaIVb microtubules shed light on isoform specific assembly
Journal, issue, pagesBiorxiv, Year 2023
Publish dateMay 7, 2024 (structure data deposition date)
AuthorsZehr EA / Roll-Mecak A
External linksBiorxiv / Search PubMed
MethodsEM (single particle)
Resolution2.9 - 3.1 Å
Structure data

44762

9bp6

EMDB-44762, PDB-9bp6:
Structure of alpha1B and betaI/IVb microtubule bound to GMPCPP
Method: EM (single particle) / Resolution: 3.1 Å

45775

9coc

EMDB-45775, PDB-9coc:
Two protofilament structure of alpha1B and betaI/IVb microtubule bound to GDP
Method: EM (single particle) / Resolution: 2.9 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-G2P:
PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER / GMP-CPP, energy-carrying molecule analogue*YM

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

Source
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN / human microtubule / tubulin isoforms / cytoskeleton

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