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Structure paper

TitleNanobody regulation of C-type inactivation in Kv1.3 channels
Journal, issue, pagesNat Commun, Year 2026
Publish dateJul 10, 2024 (structure data deposition date)
AuthorsSelvakumar P / Swartz KJ / Fernandez-Marino AI
External linksNat Commun / Search PubMed
MethodsEM (single particle)
Resolution2.97 - 3.18 Å
Structure data

45668

9cla

EMDB-45668, PDB-9cla:
Human Kv1.3 mutant-H451V
Method: EM (single particle) / Resolution: 2.97 Å

45731

9clv

EMDB-45731, PDB-9clv:
Human Kv1.3 mutant-P424G
Method: EM (single particle) / Resolution: 3.18 Å

45786

9con

EMDB-45786, PDB-9con:
Human Kv1.3-H451V with A0194009G09 nanobodies conformation 1
Method: EM (single particle) / Resolution: 3.06 Å

45922

9cty

EMDB-45922, PDB-9cty:
Human Kv1.3-H451V with A0194009G09 nanobodies conformation 2
Method: EM (single particle) / Resolution: 3.03 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

Source
  • aequorea victoria (jellyfish)
  • lama glama (llama)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Voltage gated potassium channel

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