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TitleMapping of vaccine-induced humoral responses to the Lassa virus glycoprotein reveals off-target and immunodominant responses
Journal, issue, pagesTo Be Published
Publish dateAug 24, 2023 (structure data deposition date)
AuthorsBrouwer PJM / Perrett HR / Nijhuis H / Lee W-H / Burger J / Lloyd NM / Himansu S / Beaumont T / Carfi A / Bukreyev A ...Brouwer PJM / Perrett HR / Nijhuis H / Lee W-H / Burger J / Lloyd NM / Himansu S / Beaumont T / Carfi A / Bukreyev A / Sanders RW / van Gils MJ / Ward AB
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.3 Å
Structure data

41713

8tyc

EMDB-41713, PDB-8tyc:
Lassa GPC (strain Josiah) bound to rabbit polyclonal base-targeting antibody Base-1
Method: EM (single particle) / Resolution: 3.3 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • lassa virus
  • oryctolagus cuniculus (rabbit)
  • thermotoga maritima (strain atcc 43589 / dsm 3109 / jcm 10099 / nbrc 100826 / msb8) (bacteria)
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / Lassa virus glycoprotein complex / GPC / immune complex / antibody / polyclonal antibody / base antibody / VIRAL PROTEIN / VIRAL PROTEIN-IMMUNE SYSTEM complex

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