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Structure paper

TitleThe N terminus of H3-influenza hemagglutinin as a site-of-vulnerability to neutralizing antibody
Journal, issue, pagesStructure, Year 2025
Publish dateAug 22, 2023 (structure data deposition date)
AuthorsRawi R / Morano NC / Cheung CSF / Du H / Gorman J / Prabhakaran M / Becker JE / Bylund T / Charaf S / Chen X ...Rawi R / Morano NC / Cheung CSF / Du H / Gorman J / Prabhakaran M / Becker JE / Bylund T / Charaf S / Chen X / Lee M / Harris DR / Olia AS / Ou L / Wang L / Wang S / Zhang B / Kanekiyo M / McDermott AB / Zhou T / Shapiro L / Kwong PD
External linksStructure / Search PubMed
MethodsEM (single particle) / X-ray diffraction
Resolution2.63 - 3.22 Å
Structure data

41676

8tx3

EMDB-41676, PDB-8tx3:
Fab 3864-6 in complex with influenza HA H3-VIC11
Method: EM (single particle) / Resolution: 2.99 Å

41705

8txu

EMDB-41705, PDB-8txu:
Fab 3864-10 in complex with influenza HA H3-SING16
Method: EM (single particle) / Resolution: 3.22 Å

PDB-9e69:
Antibody 5E10
Method: X-RAY DIFFRACTION / Resolution: 2.63 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
  • influenza a virus (a/victoria/361/2011(h3n2))
  • influenza a virus
  • mus musculus (house mouse)
KeywordsANTIVIRAL PROTEIN / antibody / influenza / IMMUNE SYSTEM

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