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TitleCryo-EM structures of UHRF1:nucleosome complex revealing the basis for UHRF1 binding to nucleosome and histone H3 ubiquitination
Journal, issue, pagesTo Be Published
Publish dateMar 21, 2024 (structure data deposition date)
AuthorsShikimachi R / Matsuzawa S / Onoda H / Konuma T / YAmagata A / Shirouzu M / Arita K
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.65 - 2.88 Å
Structure data

EMDB-39541: Cryo-EM map of UHRF1 in complex with nucleosome containing hemimethylated CpG site at 5'linker DNA
Method: EM (single particle) / Resolution: 2.65 Å

EMDB-39548: Cryo-EM map of UHRF1 in complex with nucleosome containing hemimethylated CpG site at 3'linker DNA
Method: EM (single particle) / Resolution: 2.88 Å

EMDB-39550: Cryo-EM map of UHRF1 in complex with nucleosome containing hemimethylated CpG site at widom601 sequence
Method: EM (single particle) / Resolution: 2.85 Å

Source
  • Homo sapiens (human)

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