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TitleStructural insights into thyrotropin-releasing hormone receptor activation by an endogenous peptide agonist or its orally administered analogue.
Journal, issue, pagesCell Res, Vol. 32, Issue 9, Page 858-861, Year 2022
Publish dateMar 29, 2022
AuthorsFan Yang / Huanhuan Zhang / Xianyu Meng / Yingge Li / Yingxin Zhou / Shenglong Ling / Demeng Sun / Pei Lv / Lei Liu / Pan Shi / Changlin Tian /
External linksCell Res / PubMed:35352031 / PubMed Central
MethodsEM (single particle)
Resolution3.19 - 3.26 Å
Structure data

32949

7x1t

EMDB-32949, PDB-7x1t:
Structure of Thyrotropin-Releasing Hormone Receptor bound with Taltirelin.
Method: EM (single particle) / Resolution: 3.26 Å

32950

7x1u

EMDB-32950, PDB-7x1u:
Structure of Thyrotropin-Releasing Hormone Receptor bound with an Endogenous Peptide Agonist TRH.
Method: EM (single particle) / Resolution: 3.19 Å

Source
  • homo sapiens (human)
  • bos taurus (domestic cattle)
  • rattus norvegicus (Norway rat)
  • synthetic construct (others)
KeywordsMEMBRANE PROTEIN / Thyrotropin-Releasing Hormone Receptor / Cryo-EM / Protirelin / agonist

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