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TitleSARS-CoV-2 spike protein (down conformation) bound with a nanobody
Journal, issue, pagesTo Be Published
Publish dateNov 11, 2022 (structure data deposition date)
AuthorsLaughlin ZL / Patel A / Ortlund EA
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.52 - 3.92 Å
Structure data

28856

8f4p

EMDB-28856, PDB-8f4p:
SARS-CoV-2 spike protein trimer (down conformation) bound with a nanobody
Method: EM (single particle) / Resolution: 3.7 Å

EMDB-28868: Overall, original map of SARS-CoV-2 spike glycoprotein trimer with RBDs in the down conformation with nanobody attached to two RBDs.
Method: EM (single particle) / Resolution: 3.52 Å

EMDB-28880: Locally refined map of SARS-CoV-2 spike glycoprotein trimer with nanobody bound to two RBDs
Method: EM (single particle) / Resolution: 3.92 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • severe acute respiratory syndrome coronavirus 2
  • lama glama (llama)
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / SARS-CoV-2 / spike / antibody / nanobody / VIRAL PROTEIN-IMMUNE SYSTEM complex

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