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TitleFab-dimerized glycan-reactive antibodies neutralize HIV and are prevalent in humans and rhesus macaques
Journal, issue, pagesbioRxiv, Vol. https://doi.org/10.1101/2020.06.30.178921, Year 2020
Publish dateDec 17, 2020 (structure data deposition date)
AuthorsWilliams WB / Meyerhoff RR / Edwards RJ / Li H / Nicely NI / Henderson R / Zhou Y / Janowska K / Mansouri K / Manne K ...Williams WB / Meyerhoff RR / Edwards RJ / Li H / Nicely NI / Henderson R / Zhou Y / Janowska K / Mansouri K / Manne K / Stalls V / Hsu AL / Borgnia MJ / Stewart-Jones G / Lee MS / Bronkema N / Perfect J / Moody MA / Wiehe K / Bradley T / Kepler TB / Alam SM / Foulger A / Bonsignori M / LaBranche CC / Montefiori DC / Seaman M / Santra S / Francica JR / Lynn GM / Aussedat B / Walkowicz WE / Laga R / Kelso G / Saunders KO / Fera D / Kwong PD / Seder RA / Bartesaghi A / Shaw GM / Acharya P / Haynes BF
External linksbioRxiv / Search PubMed
MethodsEM (single particle)
Resolution4.7 Å
Structure data

EMDB-23149:
Cryo-electron microscopy reconstruction of antibody DH898.1 Fab-dimer bound near the CD4 binding site of HIV Env SOSIP trimer CH848 10.17
Method: EM (single particle) / Resolution: 4.7 Å

Source
  • Human immunodeficiency virus 1
  • Macaca mulatta (Rhesus monkey)

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