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TitleA Novel Mode of Action Blocking Mitochondrial Translation by the Marine Compound Elatol Promotes Potent Anti-Leukemic Activit
Journal, issue, pagesTo Be Published
Publish dateFeb 5, 2024 (structure data deposition date)
AuthorsNyvltova E / Manara P / Maiti P / Singh V / Cunnigham TA / Amador LA / Rodriguez AD / Wiefels MD / Soste M / Beaton N ...Nyvltova E / Manara P / Maiti P / Singh V / Cunnigham TA / Amador LA / Rodriguez AD / Wiefels MD / Soste M / Beaton N / Amunts A / Fontanesi F / Schatz JH / Barrientos A
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.93 - 3.09 Å
Structure data

EMDB-19559: Human mitochondrial ribosome from elatol treated HEK cells (no tRNA/mRNA bound)
Method: EM (single particle) / Resolution: 3.09 Å

EMDB-19560: Human mitoribosome purified from elatol treated HEK cells (tRNAs/mRNA at partial occupancy)
Method: EM (single particle) / Resolution: 2.93 Å

Source
  • Homo sapiens (human)

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